Resultado da pesquisa (6)

Termo utilizado na pesquisa Conidiobolomicose

#1 - Conidiobolomycosis in goats

Abstract in English:

The present article presents cases of conidiobolomycosis in adult goats with clinical signs characterized by serous nasal discharge, dyspnea, apathy, and weight loss. Two goats were necropsied. Necropsy displayed increased volume on the sagittal section of the head and an ulcerated surface containing a yellow friable mass with irregular and granular consistency in the nasal septum and in the ventral nasal turbinate. One goat also presented lesions on the ear’s skin and the right pelvic limb. Microscopically, lesions were characterized by multifocal granulomas with a central necrotic area containing non-stained fungal hyphae images surrounded by a granulomatous infiltrate. Samples of the lesions examined by immunohistochemistry and polymerase chain reaction were positive for Conidiobolus lamprauges. This is the first report of conidiobolomycosis in goats, and the disease should be considered in the differential diagnoses for rhinitis and dermatitis in goats.

Abstract in Portuguese:

O presente artigo apresenta casos de conidiobolomicose em cabras adultas com sinais clínicos caracterizados por secreção nasal serosa, dispneia, apatia e perda de peso. Dois caprinos foram necropsiados. Na necropsia, em corte sagital da cabeça, foi observado aumento de volume e superfície ulcerada contendo massa amarela e friável com consistência irregular e granular no septo nasal e conchas nasais ventrais. Uma cabra apresentou também lesões na pele da orelha e no membro pélvico direito. Microscopicamente, as lesões foram caracterizadas por granulomas multifocais com área central de necrose, contendo imagens de hifas fúngicas não coradas, circundadas por infiltrado inflamatório granulomatoso. Amostras das lesões submetidas à imuno-histoquímica e reação em cadeia da polimerase foram positivas para Conidiobolus lamprauges. Este é o primeiro registro de conidiobolomicose em caprinos e deve ser considerado no diagnóstico diferencial de rinite e dermatite em caprinos.


#2 - Diseases of the nasal cavity of ruminants in Brazil, 30(10):844-854

Abstract in English:

ABSTRACT.- Portela R.A., Riet-Correa F., Garino-Junior F., Dantas A.F.M., Simões S.V.D. & Silva S.M.S. 2010. [Diseases of the nasal cavity of ruminants in Brazil.] Doenças da cavidade nasal em ruminantes no Brasil. Pesquisa Veterinária Brasileira 30(10):844-854. Hospital Veterinário, Centro de Saúde e Tecnologia Rural, Universidade Federal de Campina Grande, Campus de Patos, 58700-970 Patos, PB Brazil. E-mail: franklin.riet@pq.cnpq.br This paper reports diseases of the nasal cavity diagnosed in ruminants in the Veterinary Hospital of the Federal University of Campina Grande, in Patos, state of Paraiba, northeastern Brazil, from 2003 to 2009. During that period three cases or outbreaks of diseases of the nasal cavity were reported in cattle, three in goats and nine in sheep (out of 404 diseases diagnosed in cattle, 330 in goats, and 338 in sheep). At all are reported one case of atopic rhinitis in cattle, seven outbreaks of conidiobolomycosis and two outbreaks of rhinofacial pythiosis in sheep, two cases of protothecosis and one of nasal aspergillosis in goats, and a myxoma and a fibrosarcoma in cattle. Additionally, other diseases of the nasal cavity reported in Brazil are reviewed, including oestrosis, rhinosporidiosis, squamous cell carcinoma, and enzootic ethmoidal tumor.

Abstract in Portuguese:

RESUMO.- Portela R.A., Riet-Correa F., Garino-Junior F., Dantas A.F.M., Simões S.V.D. & Silva S.M.S. 2010. [Diseases of the nasal cavity of ruminants in Brazil.] Doenças da cavidade nasal em ruminantes no Brasil. Pesquisa Veterinária Brasileira 30(10):844-854. Hospital Veterinário, Centro de Saúde e Tecnologia Rural, Universidade Federal de Campina Grande, Campus de Patos, 58700-970 Patos, PB Brazil. E-mail: franklin.riet@pq.cnpq.br Este trabalho descreve as doenças das fossas nasais diagnosticadas em ruminantes no Hospital Veterinário da Universidade Federal de Campina Grande, em Patos, Paraíba, nos anos de 2003-2009. No período foram registrados três diagnósticos de doenças das fossas nasais de bovinos, três em caprinos e nove em ovinos (de um total de 404 diagnósticos em bovinos, 330 em caprinos e 338 em ovinos). Descrevem-se um caso de rinite atópica em bovinos, sete surtos de conidiobolomicose e dois de pitiose rinofacial em ovinos, dois casos de prototecose e um de aspergilose nasal em caprinos e um mixoma e um fibrossarcoma em bovinos. Adicionalmente, é realizada uma revisão de outras doenças das fossas nasais de ruminantes descritas em outras regiões do Brasil, incluindo oestrose, rinosporidiose, carcinoma epidermóide e tumor etmoidal enzoótico.


#3 - Conidiobolomycosis caused by Conidiobolus lamprauges in sheep in the state of Santa Catarina, Brazil, 30(7):529-532

Abstract in English:

ABSTRACT.- Furlan F.H., Lucioli J., Veronezi L.O., Fonteque J.H., Traverso S.D., Nakazato L. & Gava A. 2010. [Conidiobolomycosis caused by Conidiobolus lamprauges in sheep in the state of Santa Catarina, Brazil.] Conidiobolomicose causada por Conidiobolus lamprauges em ovinos no Estado de Santa Catarina. Pesquisa Veterinária Brasileira 30(7):529-532. Laboratório de Patologia Animal, Instituto de Ciências da Saúde, Centro Universitário de Sinop, Universidade Federal de Mato Grosso, Sinop, MT 78550-000, Brazil. E-mail: fhfurlan@gmail.com An outbreak of conidiobolomycosis affecting sheep in the State of Santa Catarina, Southern Brazil is reported. The disease occurred in six Santa Inês breed sheep from a flock of 75 during the rainy season. Common clinical signs were noisy respiration and dyspnea, serous to mucosanguineous nasal discharge and exophthalmus. At necropsy there was a dense yellow mass in the nasopharyngeal area affecting the ethmoidal region, turbinate bones and occasionally limph nodes, central nervous system and pleura. Histopathologycally there was multifocal granulomas whith an eosinophilic necrotic reaction containing ribbon type hyphae similar to zygomycetous fungi. At molecular examination Conidiobolus lamprauges DNA was detected. The clinical, epidemiological, macroscopical, microscopical and molecular aspects characterize conidiobolomycosis caused by Conidiobolus lamprauges in sheep.

Abstract in Portuguese:

RESUMO.- Furlan F.H., Lucioli J., Veronezi L.O., Fonteque J.H., Traverso S.D., Nakazato L. & Gava A. 2010. [Conidiobolomycosis caused by Conidiobolus lamprauges in sheep in the state of Santa Catarina, Brazil.] Conidiobolomicose causada por Conidiobolus lamprauges em ovinos no Estado de Santa Catarina. Pesquisa Veterinária Brasileira 30(7):529-532. Laboratório de Patologia Animal, Instituto de Ciências da Saúde, Centro Universitário de Sinop, Universidade Federal de Mato Grosso, Sinop, MT 78550-000, Brazil. E-mail: fhfurlan@gmail.com Descreve-se um surto de conidiobolomicose em ovinos no Estado de Santa Catarina. O surto ocorreu entre os meses de dezembro e março de 2006, no município de Santo Amaro da Imperatriz, região litorânea do Estado. A propriedade possuía 75 ovinos da raça Santa Inês e seis desses animais adoeceram. Clinicamente os animais doentes apresentavam dificuldade respiratória, corrimento nasal seroso a mucossanguinolento e, por vezes exolftalmia. Na necropsia verificou-se uma massa amarelada na região etmoidal e adjacências que, às vezes, atingia os linfonodos regionais, cérebro, globo ocular e pleura. Microscopicamente a massa caracterizava-se por infiltrado inflamatório granulomatoso com áreas necróticas associadas a hifas largas pouco ramificadas. Através de exame molecular detectou-se DNA de Conidiobolus lamprauges. Os aspectos clínicos, epidemiológicos, macroscópicos, microscópicos e moleculares caracterizam a conidiobolomicose causada por Conidiobolus lamprauges em ovinos.


#4 - Hemograma, proteinograma, ionograma e dosagens bioquímicas e enzimáticas de ovinos acometidos de conidiobolomicose no Nordeste do Brasil, p.17-24

Abstract in English:

ABSTRACT.- Batista M.C.S, Castro R.S., Rego E.W., Carvalho A.A., Silva S.M.S., Carvalho C.D.D. & Riet-Correa F. 2009. [Hematology and blood biochemistry in sheep with conidiobolomycosis in northeastern Brazil.] Hemograma, proteinograma, ionograma e dosagens bioquímicas e enzimáticas de ovinos acometidos de conidiobolomicose no Nordeste do Brasil. Pesquisa Veterinária Brasileira 29(1):17-24 Departamento de Morfofisiologia Veterinária da Universidade Federal do Piauí, Campus Universitário Ministro Petrônio Portella, s/n, Bairro Ininga, Teresina, PI 64049-450, Brazil. Email: cbatista@ufpi.br Hematologic values, serum levels of albumin, globulins, total proteins, calcium, phosphorus, magnesium, chloride, urea nitrogen, creatinine, total, direct and indirect bilirrubin, and serum activities of aspartate aminotransferase (AST), alkalin phosphatase (AF) and gama-glutamyltransferase (GGT) were determined in 56 hair sheep with conidiobolomycosis and 371 healthy hair sheep from the same flocks. Sheep with conidiobolomycosis had nonregenerative, normocytic and normochromic anemia, leucocytosis with neutrophilia and increased nutrophil:lymphocyte rate, moderate monocytosis, moderate thrombocytosis, hypoproteinemia (hypoglobulinemia), hypomagnesemia, hypocalcemia and increased values of phosphorus. Serum activities of AST and GGT were increased and serum activity of FA decreased. Serum values of urea and creatinine were within normal values. Hypoglycemia and hyperbilirrubinemia were also observed. These results can be used for experimental studies with the disease, for treatments trials, and to detect early cases of the disease without clinical signs. Otherwise the hematologic and blood biochemistry values of healthy sheep can be used as reference values for hair sheep in the semi-arid region of Brazil.

Abstract in Portuguese:

ABSTRACT.- Batista M.C.S, Castro R.S., Rego E.W., Carvalho A.A., Silva S.M.S., Carvalho C.D.D. & Riet-Correa F. 2009. [Hematology and blood biochemistry in sheep with conidiobolomycosis in northeastern Brazil.] Hemograma, proteinograma, ionograma e dosagens bioquímicas e enzimáticas de ovinos acometidos de conidiobolomicose no Nordeste do Brasil. Pesquisa Veterinária Brasileira 29(1):17-24 Departamento de Morfofisiologia Veterinária da Universidade Federal do Piauí, Campus Universitário Ministro Petrônio Portella, s/n, Bairro Ininga, Teresina, PI 64049-450, Brazil. Email: cbatista@ufpi.br Hematologic values, serum levels of albumin, globulins, total proteins, calcium, phosphorus, magnesium, chloride, urea nitrogen, creatinine, total, direct and indirect bilirrubin, and serum activities of aspartate aminotransferase (AST), alkalin phosphatase (AF) and gama-glutamyltransferase (GGT) were determined in 56 hair sheep with conidiobolomycosis and 371 healthy hair sheep from the same flocks. Sheep with conidiobolomycosis had nonregenerative, normocytic and normochromic anemia, leucocytosis with neutrophilia and increased nutrophil:lymphocyte rate, moderate monocytosis, moderate thrombocytosis, hypoproteinemia (hypoglobulinemia), hypomagnesemia, hypocalcemia and increased values of phosphorus. Serum activities of AST and GGT were increased and serum activity of FA decreased. Serum values of urea and creatinine were within normal values. Hypoglycemia and hyperbilirrubinemia were also observed. These results can be used for experimental studies with the disease, for treatments trials, and to detect early cases of the disease without clinical signs. Otherwise the hematologic and blood biochemistry values of healthy sheep can be used as reference values for hair sheep in the semi-arid region of Brazil.


#5 - Conidiobolomicose em ovinos no Estado de Mato Grosso, p.77-81

Abstract in English:

ABSTRACT.- Boabaid F.M., Ferreira E.V., Arruda L.P., Gasparetto N.D., Souza R.L., Silva M.C., Dutra V., Nakazato L. & Colodel E.M. 2008. [Conidiobolomycosis in sheep in the state of Mato Grosso, Brazil.] Conidiobolomicose em ovinos no Estado de Mato Grosso. Pesquisa Veterinária Brasileira 28(1):77-81. Departamento de Clínica Médica Veterinária, Faculdade de Agronomia e Medicina Veterinária, Universidade Federal de Mato Grosso, Av. Fernando Correia da Costa s/n, Bairro Coxipó, Cuiabá, MT 78068-900, Brasil. E-mail: moleta@ufmt.br The epidemiological, clinical, pathological and mycological findings of an outbreak of conidiobolomycosis in a flock of 40 Santa Ines sheep, in the state of Mato Grosso, Brazil, are reported. The illness occurred in the municipality of Nobres during January-June, 2007, resulting in death of about 30% of the affected sheep within 2-5 weeks. The clinical signs were characterized by apathy, weight loss, labored and noisy breathing with dyspnea, and mucous or serohemorrhagic nasal discharge. In three sheep there was unilateral exophthalmia, keratitis and corneal ulceration. A firm whitish, multi-lobulated, friable growth was evident in the ethmoturbinate region at the coronal sections of the head from six affected sheep. In all sheep the choana had similar nodular infiltration which resulted in local obstruction. In three of those there was exophthalmia. There was infiltration in the cribiform plate and brain (2 cases), regional lymph nodes (2), lungs (3), and abomasums (1). Microscopic findings were granulomatous inflammation of the rhinoetimoidal region, with necrosis, lymphocytic infiltration, epithelioid multinucleated giant cells and fibrovascular tissue, surrounding Splendore-Hoeppli material wich contained unstained ghost images of hyphae. The methenamine-silver stain uncover fungi hyphae, rarely ramified with bulbous dilatation in their extremities. Conidiobolus sp. was isolated from nasal tissue lesions of four sheep.

Abstract in Portuguese:

ABSTRACT.- Boabaid F.M., Ferreira E.V., Arruda L.P., Gasparetto N.D., Souza R.L., Silva M.C., Dutra V., Nakazato L. & Colodel E.M. 2008. [Conidiobolomycosis in sheep in the state of Mato Grosso, Brazil.] Conidiobolomicose em ovinos no Estado de Mato Grosso. Pesquisa Veterinária Brasileira 28(1):77-81. Departamento de Clínica Médica Veterinária, Faculdade de Agronomia e Medicina Veterinária, Universidade Federal de Mato Grosso, Av. Fernando Correia da Costa s/n, Bairro Coxipó, Cuiabá, MT 78068-900, Brasil. E-mail: moleta@ufmt.br The epidemiological, clinical, pathological and mycological findings of an outbreak of conidiobolomycosis in a flock of 40 Santa Ines sheep, in the state of Mato Grosso, Brazil, are reported. The illness occurred in the municipality of Nobres during January-June, 2007, resulting in death of about 30% of the affected sheep within 2-5 weeks. The clinical signs were characterized by apathy, weight loss, labored and noisy breathing with dyspnea, and mucous or serohemorrhagic nasal discharge. In three sheep there was unilateral exophthalmia, keratitis and corneal ulceration. A firm whitish, multi-lobulated, friable growth was evident in the ethmoturbinate region at the coronal sections of the head from six affected sheep. In all sheep the choana had similar nodular infiltration which resulted in local obstruction. In three of those there was exophthalmia. There was infiltration in the cribiform plate and brain (2 cases), regional lymph nodes (2), lungs (3), and abomasums (1). Microscopic findings were granulomatous inflammation of the rhinoetimoidal region, with necrosis, lymphocytic infiltration, epithelioid multinucleated giant cells and fibrovascular tissue, surrounding Splendore-Hoeppli material wich contained unstained ghost images of hyphae. The methenamine-silver stain uncover fungi hyphae, rarely ramified with bulbous dilatation in their extremities. Conidiobolus sp. was isolated from nasal tissue lesions of four sheep.


#6 - Epidemiologia e sinais clínicos da conidiobolomicose em ovinos no Estado do Piauí, p.184-190

Abstract in English:

ABSTRACT.- Silva S.M.M.S., Castro R.S., Costa F.A.L., Vasconcelos A.C., Batista M.C.S., Riet-Correa F. & Carvalho E.M.S. 2007. [Epidemiology and symptoms of conidiobolomycosis in sheep in the State of Piauí, Brazil.] Epidemiologia e sinais clínicos da conidiobolomicose em ovinos no Estado do Piauí. Pesquisa Veterinária Brasileira 27(4):184-190. Departamento de Clínica e Cirurgia, Centro de Ciências Agrárias, Universidade Federal do Piauí, Campus da Socopo s/n, Teresina, PI 64049-550, Brazil. E-mail: silvanammss@ufpi.br Conidiobolomycosis is reported in 25 farms, from January 2002 to December 2004, in the state of Piauí. The disease affects only sheep, mainly in April-June. The mean morbidity rate was 2.80%, but was higher in the first semester (2.1%), during the raining period, than in the second one (0.69%), during the dry period. Morbidity rate among flocks varied from 0.1-14.3%. Case fatality rate was 100%, and the clinical manifestation period varied from 1-5 weeks. Clinical signs were serous, mucous and/or bloody nasal secretion, respiratory distress, snoring respiration, cranium-facial asymmetry, exophthalmia, fever and progressive emaciation. Marked depression, sometimes with the head down or head pressing was observed in some cases. Gross, microscopic and ultrastructural lesions and identification of the agent are reported elsewhere. This is the first report of conidiobolomycosis in Brazil, which is endemic and has a high frequency in sheep in the State of Piauí, associated with high rainfalls (1000-1600mm annually) and high temperature (19-36°C).

Abstract in Portuguese:

ABSTRACT.- Silva S.M.M.S., Castro R.S., Costa F.A.L., Vasconcelos A.C., Batista M.C.S., Riet-Correa F. & Carvalho E.M.S. 2007. [Epidemiology and symptoms of conidiobolomycosis in sheep in the State of Piauí, Brazil.] Epidemiologia e sinais clínicos da conidiobolomicose em ovinos no Estado do Piauí. Pesquisa Veterinária Brasileira 27(4):184-190. Departamento de Clínica e Cirurgia, Centro de Ciências Agrárias, Universidade Federal do Piauí, Campus da Socopo s/n, Teresina, PI 64049-550, Brazil. E-mail: silvanammss@ufpi.br Conidiobolomycosis is reported in 25 farms, from January 2002 to December 2004, in the state of Piauí. The disease affects only sheep, mainly in April-June. The mean morbidity rate was 2.80%, but was higher in the first semester (2.1%), during the raining period, than in the second one (0.69%), during the dry period. Morbidity rate among flocks varied from 0.1-14.3%. Case fatality rate was 100%, and the clinical manifestation period varied from 1-5 weeks. Clinical signs were serous, mucous and/or bloody nasal secretion, respiratory distress, snoring respiration, cranium-facial asymmetry, exophthalmia, fever and progressive emaciation. Marked depression, sometimes with the head down or head pressing was observed in some cases. Gross, microscopic and ultrastructural lesions and identification of the agent are reported elsewhere. This is the first report of conidiobolomycosis in Brazil, which is endemic and has a high frequency in sheep in the State of Piauí, associated with high rainfalls (1000-1600mm annually) and high temperature (19-36°C).


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